| 1. Round | 03/08/2002 | Gallos Blancos (old) | - | Real San Luis | 1:1 | ||||
| 2. Round | 09/08/2002 | Real San Luis | - | Puebla FC | 1:0 | ||||
| 3. Round | 17/08/2002 | CF América | - | Real San Luis | 2:1 | ||||
| 4. Round | 23/08/2002 | Real San Luis | - | Jaguares Chiapas | 0:1 |  |
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| 5. Round | 30/08/2002 | Cruz Azul | - | Real San Luis | 0:1 | ||||
| 6. Round | 06/09/2002 | Real San Luis | - | UAG Tecos | 0:0 | ||||
| 7. Round | 10/09/2002 | UANL Tigres | - | Real San Luis | 0:4 | ||||
| 8. Round | 13/09/2002 | Real San Luis | - | CF Pachuca | 2:4 |  |
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| 11. Round | 04/10/2002 | Real San Luis | - | Santos Laguna | 1:1 | ||||
| 12. Round | 12/10/2002 | Club Necaxa | - | Real San Luis | 3:2 | ||||
| 13. Round | 15/10/2002 | Real San Luis | - | Atlante | 2:2 | ||||
| 14. Round | 19/10/2002 | Monarcas Morelia | - | Real San Luis | 3:2 | ||||
| 15. Round | 26/10/2002 | Real San Luis | - | Pumas UNAM | 6:3 | |
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| 16. Round | 01/11/2002 | Veracruz (old) | - | Real San Luis | 3:1 | ||||
| 18. Round | 15/11/2002 | Deportivo Toluca | - | Real San Luis | 3:1 |
Mexico