| 6. Round | 29/08/2010 | Real Mamoré | - | Oriente Petrolero | 3:2 |  |
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| 7. Round | 06/09/2010 | Club Aurora | - | Real Mamoré | 3:0 | ||||
| 8. Round | 10/09/2010 | Real Mamoré | - | Bolívar | 2:1 | ||||
| 9. Round | 12/09/2010 | La Paz FC | - | Real Mamoré | 1:0 | ||||
| 10. Round | 18/09/2010 | Club San José | - | Real Mamoré | 1:0 | ||||
| 13. Round | 28/10/2010 | Jorge Wilstermann | - | Real Mamoré | 2:0 | ||||
| 21. Round | 21/11/2010 | Real Mamoré | - | Club San José | 3:0 | |
Bolivia