| 2. Round | 01/09/2012 | Danubio | - | Progreso | 1:4 | ||||
| 3. Round | 16/09/2012 | Danubio | - | Montevideo Wanderers | 2:4 | ||||
| 4. Round | 23/09/2012 | Juventud de Las Piedras | - | Danubio | 0:0 | ||||
| 6. Round | 07/10/2012 | Nacional | - | Danubio | 2:1 | ||||
| 8. Round | 21/10/2012 | Defensor Sporting | - | Danubio | 3:1 | ||||
| 9. Round | 27/10/2012 | Danubio | - | CA Cerro | 1:1 |  |
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| 10. Round | 03/11/2012 | Racing | - | Danubio | 2:2 | ||||
| 11. Round | 10/11/2012 | Central Español | - | Danubio | 1:0 | |
Uruguay