| 1. Round | 21/09/2020 | Cimarrones de Sonora II | - | Mazorqueros | 1:2 | ||||
| 2. Round | 25/09/2020 | Mazorqueros | - | Saltillo FC | 1:1 | ||||
| 3. Round | 04/10/2020 | Leones Negros II | - | Mazorqueros | 1:2 | ||||
| 4. Round | 12/10/2020 | Mazorqueros | - | Tecos Fútbol Club | 2:0 | ||||
| 5. Round | 17/10/2020 | Mineros de Fresnillo FC | - | Mazorqueros | 3:1 | ||||
| 6. Round | 24/10/2020 | Mazorqueros | - | Colima FC | 0:2 | ||||
| 7. Round | 09/11/2020 | Mazorqueros | - | Atlético San Luis II | 1:0 | ||||
| 9. Round | 22/11/2020 | Mazorqueros | - | Gavilanes de Matamoros | 1:2 |  |
|||
| 10. Round | 06/12/2020 | Tuzos de la UAZ | - | Mazorqueros | 3:1 | |
|||
| 11. Round | 12/12/2020 | Mazorqueros | - | Alacranes de Durango | 1:0 | ||||
| 18. Round | 05/03/2021 | Atlético San Luis II | - | Mazorqueros | 2:1 | ||||
| 19. Round | 13/03/2021 | Mazorqueros | - | Reboceros de La Piedad | 1:1 |
Mexico