| 3. Round | 04/10/2020 | Leones Negros II | - | Mazorqueros | 1:2 | ||||
| 7. Round | 07/11/2020 | Leones Negros II | - | Tuzos de la UAZ | 2:2 | ||||
| 9. Round | 20/11/2020 | Leones Negros II | - | Cimarrones de Sonora II | 1:1 | ||||
| 10. Round | 05/12/2020 | Saltillo FC | - | Leones Negros II | 2:0 | ||||
| 12. Round | 16/01/2021 | Tecos Fútbol Club | - | Leones Negros II | 2:3 | ||||
| 13. Round | 23/01/2021 | Leones Negros II | - | Mineros de Fresnillo FC | 2:2 | ||||
| 14. Round | 29/01/2021 | Mazorqueros | - | Leones Negros II | 1:0 | ||||
| 15. Round | 07/02/2021 | Leones Negros II | - | Atlético San Luis II | 1:2 |  |
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| 16. Round | 12/02/2021 | Reboceros de La Piedad | - | Leones Negros II | 4:0 |
Mexico