| 4. Round | 04/08/2012 | 1. FC Tatran Prešov | - | MFK Ružomberok | 2:0 |  |
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| 5. Round | 11/08/2012 | Zlaté Moravce | - | 1. FC Tatran Prešov | 2:0 | ||||
| 6. Round | 18/08/2012 | 1. FC Tatran Prešov | - | FC Nitra | 1:0 | ||||
| 7. Round | 25/08/2012 | FK Dukla Banská Bystrica | - | 1. FC Tatran Prešov | 0:0 | ||||
| 8. Round | 01/09/2012 | Spartak Myjava | - | 1. FC Tatran Prešov | 2:0 | ||||
| 9. Round | 15/09/2012 | 1. FC Tatran Prešov | - | MFK Košice | 0:0 | ||||
| 10. Round | 22/09/2012 | MŠK Žilina | - | 1. FC Tatran Prešov | 3:0 | ||||
| 11. Round | 29/09/2012 | 1. FC Tatran Prešov | - | Spartak Trnava | 2:1 | ||||
| 12. Round | 06/10/2012 | 1. FC Tatran Prešov | - | Slovan Bratislava | 0:0 | ||||
| 13. Round | 20/10/2012 | FK Senica | - | 1. FC Tatran Prešov | 2:0 |  |
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| 14. Round | 27/10/2012 | 1. FC Tatran Prešov | - | AS Trenčín | 1:2 | |
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| 17. Round | 17/11/2012 | FC Nitra | - | 1. FC Tatran Prešov | 4:1 | |
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| 18. Round | 24/11/2012 | 1. FC Tatran Prešov | - | FK Dukla Banská Bystrica | 1:0 | ||||
| 19. Round | 01/12/2012 | 1. FC Tatran Prešov | - | Spartak Myjava | 2:1 |
Slovakia