| 1. Round | 29/08/2010 | Real Betis | - | Granada CF | 4:1 | ||||
| 2. Round | 04/09/2010 | Recreativo Huelva | - | Real Betis | 1:3 |  |
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| 3. Round | 11/09/2010 | Elche CF | - | Real Betis | 0:2 | ||||
| 4. Round | 19/09/2010 | Real Betis | - | Real Valladolid | 2:1 | ||||
| 6. Round | 02/10/2010 | Real Betis | - | SD Ponferradina | 3:0 | ||||
| 7. Round | 09/10/2010 | UD Las Palmas | - | Real Betis | 2:2 |
Argentina
Italy