| 1. Round | 01/07/2022 | Club Necaxa [U18] | - | Deportivo Toluca [U18] | 1:1 | ||||
| 2. Round | 10/07/2022 | Gallos Blancos [U18] | - | Club Necaxa [U18] | 1:0 | ||||
| 3. Round | 17/07/2022 | Pumas UNAM [U18] | - | Club Necaxa [U18] | 2:3 | ||||
| 4. Round | 22/07/2022 | Club Necaxa [U18] | - | FC Juárez [U18] | 3:0 |  |
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| 5. Round | 27/07/2022 | Club Necaxa [U18] | - | CF Pachuca [U18] | 1:2 | ||||
| 6. Round | 30/07/2022 | Cruz Azul [U18] | - | Club Necaxa [U18] | 0:5 | ||||
| 8. Round | 12/08/2022 | Club Necaxa [U18] | - | CF Monterrey [U18] | 1:1 | ||||
| 12. Round | 02/09/2022 | Club Necaxa [U18] | - | Club León [U18] | 1:1 | ||||
| 13. Round | 06/09/2022 | Santos Laguna [U18] | - | Club Necaxa [U18] | 3:0 | |
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| 14. Round | 10/09/2022 | Club Necaxa [U18] | - | CF América [U18] | 0:4 | ||||
| 15. Round | 18/09/2022 | Club Tijuana [U18] | - | Club Necaxa [U18] | 2:1 | ||||
| 16. Round | 24/09/2022 | Club Necaxa [U18] | - | Mazatlán FC [U18] | 1:2 |
Mexico