| 7. Round | 18/02/2021 | Atlético San Luis [U20] | - | Santos Laguna [U20] | 0:4 |  |
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| 9. Round | 02/03/2021 | Atlas Guadalajara [U20] | - | Atlético San Luis [U20] | 2:0 |  |
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| 10. Round | 05/03/2021 | Atlético San Luis [U20] | - | Deportivo Toluca [U20] | 1:2 | ||||
| 11. Round | 14/03/2021 | Gallos Blancos [U20] | - | Atlético San Luis [U20] | 0:1 |
Uruguay