| 1. Round | 09/01/2021 | UANL Tigres [U17] | - | Club León [U17] | 3:0 | ||||
| 2. Round | 17/01/2021 | Santos Laguna [U17] | - | UANL Tigres [U17] | 2:3 | ||||
| 7. Round | 21/02/2021 | UANL Tigres [U17] | - | Club Tijuana [U17] | 1:0 | ||||
| 8. Round | 25/02/2021 | Atlético San Luis [U17] | - | UANL Tigres [U17] | 2:2 | ||||
| 9. Round | 02/03/2021 | UANL Tigres [U17] | - | Deportivo Toluca [U17] | 0:1 | ||||
| 10. Round | 05/03/2021 | Puebla FC [U17] | - | UANL Tigres [U17] | 2:2 | ||||
| 11. Round | 13/03/2021 | UANL Tigres [U17] | - | Mazatlán FC [U17] | 2:3 |  |
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| 12. Round | 18/03/2021 | CF Pachuca [U17] | - | UANL Tigres [U17] | 2:2 | ||||
| 13. Round | 04/04/2021 | Gallos Blancos [U17] | - | UANL Tigres [U17] | 1:0 | ||||
| 14. Round | 10/04/2021 | UANL Tigres [U17] | - | CF América [U17] | 3:3 | ||||
| 5. Round | 14/04/2021 | FC Juárez [U17] | - | UANL Tigres [U17] | 0:1 | ||||
| 15. Round | 18/04/2021 | Pumas UNAM [U17] | - | UANL Tigres [U17] | 4:0 | ||||
| 16. Round | 24/04/2021 | UANL Tigres [U17] | - | CF Monterrey [U17] | 2:1 | ||||
| 17. Round | 01/05/2021 | Deportivo Guadalajara [U17] | - | UANL Tigres [U17] | 1:0 |
Mexico