| 3. Round | 22/01/2012 | Deportivo Guadalajara | - | Club Tijuana | 0:2 | ||||
| 5. Round | 05/02/2012 | Puebla FC | - | Club Tijuana | 1:1 | ||||
| 6. Round | 12/02/2012 | Club Tijuana | - | Cruz Azul | 0:0 | ||||
| 7. Round | 18/02/2012 | Gallos Blancos (old) | - | Club Tijuana | 0:2 | ||||
| 8. Round | 26/02/2012 | Club Tijuana | - | Deportivo Toluca | 1:1 |  |
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| 9. Round | 03/03/2012 | Estudiantes Tecos | - | Club Tijuana | 0:2 | ||||
| 10. Round | 10/03/2012 | Club Tijuana | - | CF América | 1:1 | ||||
| 11. Round | 18/03/2012 | UANL Tigres | - | Club Tijuana | 1:0 | ||||
| 12. Round | 25/03/2012 | Club Tijuana | - | Atlas Guadalajara | 2:0 | ||||
| 13. Round | 31/03/2012 | CF Pachuca | - | Club Tijuana | 1:0 | |
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| 14. Round | 08/04/2012 | Club Tijuana | - | Atlante | 2:1 | ||||
| 15. Round | 14/04/2012 | Jaguares Chiapas | - | Club Tijuana | 0:0 | ||||
| 16. Round | 21/04/2012 | Club San Luis | - | Club Tijuana | 0:1 |
Mexico