| 1. Round | 06/01/2013 | Puebla FC | - | Club Tijuana | 1:2 | ||||
| 2. Round | 13/01/2013 | Club Tijuana | - | Club León | 1:0 | ||||
| 3. Round | 20/01/2013 | Pumas UNAM | - | Club Tijuana | 1:2 | ||||
| 4. Round | 27/01/2013 | Club Tijuana | - | CF Pachuca | 2:0 | ||||
| 5. Round | 03/02/2013 | UANL Tigres | - | Club Tijuana | 2:2 | ||||
| 6. Round | 10/02/2013 | Club Tijuana | - | CF América | 1:2 | ||||
| 7. Round | 16/02/2013 | Jaguares Chiapas | - | Club Tijuana | 2:0 |  |
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| 8. Round | 24/02/2013 | Club Tijuana | - | Atlante | 2:0 | |
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| 11. Round | 17/03/2013 | Club Tijuana | - | CF Monterrey | 2:2 | |
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| 12. Round | 30/03/2013 | Deportivo Toluca | - | Club Tijuana | 1:0 | ||||
| 13. Round | 07/04/2013 | Club Tijuana | - | Santos Laguna | 0:0 | ||||
| 14. Round | 13/04/2013 | Cruz Azul | - | Club Tijuana | 5:0 | ||||
| 15. Round | 21/04/2013 | Club Tijuana | - | Monarcas Morelia | 1:2 | |
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| 17. Round | 04/05/2013 | Club Tijuana | - | Deportivo Guadalajara | 4:0 |
Mexico