| 1. Round | 25/08/2021 | Sint-Truidense VV [U18] | - | Club Brugge KV [U18] | 1:1 | ||||
| 2. Round | 28/08/2021 | Club Brugge KV [U18] | - | Standard Liège [U18] | 2:1 | ||||
| 6. Round | 25/09/2021 | KAA Gent [U18] | - | Club Brugge KV [U18] | 2:2 |  |
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| 9. Round | 16/10/2021 | Club Brugge KV [U18] | - | KRC Genk [U18] | 5:3 | ||||
| 10. Round | 23/10/2021 | Royal Antwerp FC [U18] | - | Club Brugge KV [U18] | 0:2 | ||||
| 3. Round | 27/10/2021 | Club Brugge KV [U18] | - | KV Mechelen [U18] | 8:0 | |
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| 11. Round | 06/11/2021 | Club Brugge KV [U18] | - | Oud-Heverlee Leuven [U18] | 4:0 | |
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| 18. Round | 05/02/2022 | Sporting Charleroi [U18] | - | Club Brugge KV [U18] | 0:3 |
Belgium