| 1. Round | 03/07/2022 | Pumas UNAM [U18] | - | Club Tijuana [U18] | 1:0 | ||||
| 3. Round | 17/07/2022 | Pumas UNAM [U18] | - | Club Necaxa [U18] | 2:3 | ||||
| 6. Round | 30/07/2022 | Pumas UNAM [U18] | - | CF Monterrey [U18] | 2:1 | ||||
| 7. Round | 06/08/2022 | Puebla FC [U18] | - | Pumas UNAM [U18] | 1:0 | ||||
| 8. Round | 13/08/2022 | Pumas UNAM [U18] | - | CF América [U18] | 1:2 | ||||
| 9. Round | 18/08/2022 | Atlético San Luis [U18] | - | Pumas UNAM [U18] | 2:1 | ||||
| 10. Round | 21/08/2022 | Pumas UNAM [U18] | - | Santos Laguna [U18] | 2:0 | ||||
| 16. Round | 24/08/2022 | Pumas UNAM [U18] | - | UANL Tigres [U18] | 1:1 | ||||
| 15. Round | 18/09/2022 | Pumas UNAM [U18] | - | Cruz Azul [U18] | 0:0 |
Mexico