| 2. Round | 22/04/2022 | Delfín SC [U19] | - | Guayaquil City [U19] | 1:2 | ||||
| 4. Round | 14/05/2022 | Guayaquil City [U19] | - | Manta FC [U19] | 1:2 | ||||
| 5. Round | 28/05/2022 | Atlético Santo Domingo [U19] | - | Guayaquil City [U19] | 0:1 | ||||
| 7. Round | 08/07/2022 | Guayaquil City [U19] | - | Delfín SC [U19] | 1:1 |  |
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| 10. Round | 05/08/2022 | Guayaquil City [U19] | - | Atlético Santo Domingo [U19] | 0:1 |
Ecuador