| 2. Round | 01/09/2021 | FC Roskilde | - | Odense BK | 1:2 | ||||
| 3. Round | 21/09/2021 | FC Helsingør | - | Odense BK | 0:3 |  |
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| Round of 16 | 27/10/2021 | FC Nordsjælland | - | Odense BK | 1:4 aet | ||||
| Quarter-finals | 05/12/2021 | Randers FC | - | Odense BK | 0:2 | ||||
| Quarter-finals | 12/12/2021 | Odense BK | - | Randers FC | 1:2 | ||||
| Semi-finals | 27/04/2022 | SønderjyskE | - | Odense BK | 1:2 | ||||
| Semi-finals | 05/05/2022 | Odense BK | - | SønderjyskE | 3:0 | ||||
| Final | 26/05/2022 | Odense BK | - | FC Midtjylland | 3:4 pso |
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