| 1. Round | 15/08/1981 | Willem II | - | AFC Ajax | 1:7 |  |
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| 2. Round | 18/08/1981 | AFC Ajax | - | Feyenoord | 1:1 | ||||
| 3. Round | 22/08/1981 | AFC Ajax | - | PEC Zwolle | 5:1 | ||||
| 4. Round | 25/08/1981 | FC Twente | - | AFC Ajax | 2:1 | ||||
| 5. Round | 29/08/1981 | AFC Ajax | - | De Graafschap | 9:1 | |
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| 6. Round | 11/09/1981 | MVV | - | AFC Ajax | 0:2 |  |
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| 7. Round | 18/09/1981 | FC Den Haag | - | AFC Ajax | 1:3 | ||||
| 8. Round | 25/09/1981 | AFC Ajax | - | FC Groningen | 6:1 | |
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| 9. Round | 04/10/1981 | Sparta Rotterdam | - | AFC Ajax | 5:3 | ||||
| 11. Round | 24/10/1981 | PSV Eindhoven | - | AFC Ajax | 3:0 | ||||
| 12. Round | 07/11/1981 | AFC Ajax | - | Go Ahead Eagles | 4:1 | ||||
| 13. Round | 10/11/1981 | FC Utrecht | - | AFC Ajax | 3:5 | ||||
| 14. Round | 21/11/1981 | AFC Ajax | - | Roda JC Kerkrade | 3:2 | ||||
| 15. Round | 27/11/1981 | AZ '67 Alkmaar | - | AFC Ajax | 1:0 | |
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| 20. Round | 12/02/1982 | PEC Zwolle | - | AFC Ajax | 1:3 | ||||
| 26. Round | 05/04/1982 | AFC Ajax | - | Sparta Rotterdam | 5:1 | |
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| 28. Round | 17/04/1982 | AFC Ajax | - | PSV Eindhoven | 3:0 | ||||
| 30. Round | 01/05/1982 | AFC Ajax | - | FC Utrecht | 1:0 | ||||
| 32. Round | 14/05/1982 | AFC Ajax | - | AZ '67 Alkmaar | 3:2 | |
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