| 1. Round | 15/08/2015 | Plaza Colonia | - | Rentistas | 1:2 | ||||
| 2. Round | 23/08/2015 | Liverpool | - | Plaza Colonia | 1:2 | ||||
| 3. Round | 29/08/2015 | Plaza Colonia | - | Villa Teresa | 0:1 | ||||
| 4. Round | 06/09/2015 | Nacional | - | Plaza Colonia | 1:0 | ||||
| 5. Round | 13/09/2015 | Plaza Colonia | - | Montevideo Wanderers | 1:1 | ||||
| 6. Round | 20/09/2015 | Plaza Colonia | - | River Plate | 3:2 | ||||
| 7. Round | 27/09/2015 | Juventud de Las Piedras | - | Plaza Colonia | 1:1 | ||||
| 8. Round | 04/10/2015 | Plaza Colonia | - | CA Cerro | 0:1 | ||||
| 9. Round | 18/10/2015 | El Tanque Sisley | - | Plaza Colonia | 0:1 | ||||
| 10. Round | 24/10/2015 | Plaza Colonia | - | Defensor Sporting | 0:0 | ||||
| 11. Round | 31/10/2015 | Fénix | - | Plaza Colonia | 0:0 | ||||
| 12. Round | 06/11/2015 | Plaza Colonia | - | Sud América | 1:1 |  |
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| 13. Round | 22/11/2015 | Racing | - | Plaza Colonia | 2:2 | ||||
| 14. Round | 28/11/2015 | Plaza Colonia | - | Peñarol | 1:1 |
Uruguay