| 5. Round | 09/02/2020 | Real Potosí | - | Club San José | 2:1 | ||||
| 9. Round | 27/02/2020 | Jorge Wilstermann | - | Club San José | 1:2 | ||||
| 10. Round | 01/03/2020 | Club San José | - | Club Aurora | 1:0 |  |
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| 1. Round | 05/03/2020 | The Strongest | - | Club San José | 3:0 | ||||
| 11. Round | 08/03/2020 | Club San José | - | Oriente Petrolero | 4:1 | ||||
| 12. Round | 12/03/2020 | Club San José | - | Blooming | 1:0 | ||||
| 13. Round | 28/11/2020 | Atlético Palmaflor | - | Club San José | 5:0 | ||||
| 14. Round | 30/11/2020 | Club San José | - | The Strongest | 1:1 | ||||
| 15. Round | 04/12/2020 | Bolívar | - | Club San José | 2:0 | ||||
| 19. Round | 13/12/2020 | Nacional Potosí | - | Club San José | 3:2 | ||||
| 20. Round | 17/12/2020 | Club San José | - | Always Ready | 1:3 | |
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| 22. Round | 22/12/2020 | Club San José | - | Jorge Wilstermann | 0:2 |
Bolivia