| 2. Round | 01/04/2022 | Universidad Católica [Women] | - | Guayaquil City [Women] | 5:0 | ||||
| 4. Round | 23/04/2022 | Técnico Universitario [Women] | - | Guayaquil City [Women] | 0:1 | ||||
| 6. Round | 09/05/2022 | UPS Carneras [Women] | - | Guayaquil City [Women] | 3:1 | ||||
| 7. Round | 15/05/2022 | Guayaquil City [Women] | - | Deportivo Ibarra [Women] | 0:4 | ||||
| 8. Round | 22/05/2022 | Guayaquil City [Women] | - | El Nacional [Women] | 1:2 |  |
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| 9. Round | 28/05/2022 | Guayaquil City [Women] | - | Universidad Católica [Women] | 1:3 | ||||
| 11. Round | 11/06/2022 | Guayaquil City [Women] | - | Técnico Universitario [Women] | 1:2 | ||||
| 12. Round | 23/07/2022 | Barcelona [Women] | - | Guayaquil City [Women] | 6:1 |
Ecuador