| 1. Round | 26/03/2022 | El Nacional [Women] | - | Guayaquil City [Women] | 2:0 | ||||
| 2. Round | 01/04/2022 | Universidad Católica [Women] | - | Guayaquil City [Women] | 5:0 |  |
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| 3. Round | 15/04/2022 | Guayaquil City [Women] | - | LDU Quito [Women] | 1:4 | ||||
| 11. Round | 11/06/2022 | Guayaquil City [Women] | - | Técnico Universitario [Women] | 1:2 | ||||
| 12. Round | 23/07/2022 | Barcelona [Women] | - | Guayaquil City [Women] | 6:1 | ||||
| 13. Round | 30/07/2022 | Guayaquil City [Women] | - | UPS Carneras [Women] | 4:0 |  |
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| 14. Round | 05/08/2022 | Deportivo Ibarra [Women] | - | Guayaquil City [Women] | 8:0 |
Ecuador