| 1. Round | 07/01/2023 | Deportivo Guadalajara [Women] | - | Pumas UNAM [Women] | 5:1 |  |
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| 2. Round | 16/01/2023 | Club Necaxa [Women] | - | Deportivo Guadalajara [Women] | 1:4 | ||||
| 3. Round | 24/01/2023 | Santos Laguna [Women] | - | Deportivo Guadalajara [Women] | 1:2 | ||||
| 4. Round | 31/01/2023 | Deportivo Guadalajara [Women] | - | FC Juárez [Women] | 2:1 | ||||
| 5. Round | 03/02/2023 | Deportivo Toluca [Women] | - | Deportivo Guadalajara [Women] | 0:0 | ||||
| 6. Round | 10/02/2023 | Deportivo Guadalajara [Women] | - | Puebla FC [Women] | 2:1 | |
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| 11. Round | 25/03/2023 | CF América [Women] | - | Deportivo Guadalajara [Women] | 2:0 | ||||
| 12. Round | 31/03/2023 | Deportivo Guadalajara [Women] | - | Atlético San Luis [Women] | 4:0 |
Mexico