| 22. Round | 26/01/2018 | FC Dordrecht | - | FC Oss | 2:0 | ||||
| 23. Round | 05/02/2018 | AZ Alkmaar (J) | - | FC Oss | 3:1 | ||||
| 24. Round | 09/02/2018 | FC Oss | - | Almere City FC | 5:1 | ||||
| 25. Round | 19/02/2018 | Jong Ajax | - | FC Oss | 2:0 | ||||
| 26. Round | 23/02/2018 | Go Ahead Eagles | - | FC Oss | 2:1 | ||||
| 27. Round | 02/03/2018 | FC Oss | - | SC Cambuur | 2:1 | ||||
| 28. Round | 09/03/2018 | FC Den Bosch | - | FC Oss | 0:0 | ||||
| 30. Round | 16/03/2018 | FC Oss | - | Fortuna Sittard | 1:2 |  |
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| 31. Round | 23/03/2018 | Helmond Sport | - | FC Oss | 2:1 | ||||
| 32. Round | 30/03/2018 | FC Oss | - | Telstar | 0:0 | |
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| 33. Round | 02/04/2018 | Jong PSV | - | FC Oss | 5:1 | ||||
| 34. Round | 06/04/2018 | FC Oss | - | RKC Waalwijk | 3:1 | ||||
| 35. Round | 09/04/2018 | NEC Nijmegen | - | FC Oss | 2:1 | ||||
| 36. Round | 13/04/2018 | FC Oss | - | De Graafschap | 1:4 | ||||
| 37. Round | 20/04/2018 | MVV | - | FC Oss | 1:1 | ||||
| 38. Round | 28/04/2018 | FC Oss | - | FC Eindhoven | 1:1 |
Netherlands