| 1. Round | 10/03/2012 | Colorado Rapids | - | Columbus Crew | 2:0 | ||||
| 1. Round | 18/03/2012 | Philadelphia Union | - | Colorado Rapids | 1:2 | ||||
| 1. Round | 25/03/2012 | New York RB | - | Colorado Rapids | 4:1 | ||||
| 2. Round | 02/04/2012 | Colorado Rapids | - | Chicago Fire | 2:0 | ||||
| 2. Round | 08/04/2012 | Real Salt Lake | - | Colorado Rapids | 2:0 | ||||
| 2. Round | 14/04/2012 | Seattle Sounders | - | Colorado Rapids | 1:0 | ||||
| 2. Round | 22/04/2012 | Colorado Rapids | - | Los Angeles Galaxy | 1:2 |  |
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| 2. Round | 29/04/2012 | Colorado Rapids | - | CD Chivas | 4:0 | ||||
| 3. Round | 07/05/2012 | FC Dallas | - | Colorado Rapids | 0:2 | ||||
| 3. Round | 20/05/2012 | Colorado Rapids | - | Sporting Kansas City | 2:2 |  |
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| 3. Round | 27/05/2012 | Colorado Rapids | - | Impact de Montréal | 3:2 | ||||
| 4. Round | 17/06/2012 | Vancouver Whitecaps | - | Colorado Rapids | 1:0 |
Japan