| 1. Round | 30/07/2017 | North Carolina FC | - | Puerto Rico FC | 1:1 | ||||
| 3. Round | 17/09/2017 | North Carolina FC | - | Puerto Rico FC | 0:0 | ||||
| 4. Round | 05/10/2017 | Indy Eleven | - | Puerto Rico FC | 2:1 | ||||
| 4. Round | 08/10/2017 | Puerto Rico FC | - | North Carolina FC | 0:1 | ||||
| 4. Round | 15/10/2017 | San Francisco Deltas | - | Puerto Rico FC | 3:0 |  |
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| 4. Round | 19/10/2017 | Puerto Rico FC | - | New York Cosmos | 1:4 | ||||
| 4. Round | 21/10/2017 | Puerto Rico FC | - | Indy Eleven | 2:1 | ||||
| 4. Round | 26/10/2017 | Puerto Rico FC | - | FC Edmonton | 2:0 |
USA