| 1. Round | 22/08/1981 | TJ Lokomotíva Košice | - | ASVS Dukla Praha | 1:2 | ||||
| 2. Round | 26/08/1981 | TJ Internacionál Slovnaft Bratislava | - | TJ Lokomotíva Košice | 0:0 | ||||
| 3. Round | 29/08/1981 | TJ Lokomotíva Košice | - | SK Slavia Praha IPS | 5:1 | ||||
| 4. Round | 02/09/1981 | ASVŠ Dukla Banská Bystrica | - | TJ Lokomotíva Košice | 0:1 | ||||
| 5. Round | 13/09/1981 | TJ Lokomotíva Košice | - | TJ ZŤS Petržalka | 2:0 |  |
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| 8. Round | 11/10/1981 | TJ Lokomotíva Košice | - | TJ Bohemians ČKD Praha | 3:2 | ||||
| 9. Round | 18/10/1981 | TJ Slovan ChZJD Bratislava | - | TJ Lokomotíva Košice | 0:1 | ||||
| 11. Round | 08/11/1981 | TJ Spartak TAZ Trnava | - | TJ Lokomotíva Košice | 0:0 | ||||
| 12. Round | 15/11/1981 | TJ Lokomotíva Košice | - | TJ Plastika Nitra | 2:0 | ||||
| 13. Round | 21/11/1981 | TJ Zbrojovka Brno | - | TJ Lokomotíva Košice | 2:1 |  |
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| 14. Round | 06/12/1981 | TJ Lokomotíva Košice | - | TJ Vítkovice | 0:0 | ||||
| 15. Round | 13/12/1981 | TJ Rudá Hvězda Cheb | - | TJ Lokomotíva Košice | 2:1 |
Slovakia