| 1. Round | 03/09/2022 | Twente/Heracles [U21] | - | NAC Breda [U21] | 6:2 | ||||
| 2. Round | 10/09/2022 | NAC Breda [U21] | - | Go Ahead Eagles [U21] | 4:2 |  |
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| 3. Round | 17/09/2022 | FC Den Bosch [U21] | - | NAC Breda [U21] | 1:2 | ||||
| 4. Round | 01/10/2022 | NAC Breda [U21] | - | NEC Nijmegen [U21] | 4:2 | ||||
| 5. Round | 08/10/2022 | Vitesse [U21] | - | NAC Breda [U21] | 0:2 |  |
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| 6. Round | 15/10/2022 | VVV-Venlo [U21] | - | NAC Breda [U21] | 1:6 | ||||
| 7. Round | 22/10/2022 | NAC Breda [U21] | - | Roda JC Kerkrade [U21] | 1:0 | ||||
| 8. Round | 29/10/2022 | NAC Breda [U21] | - | Twente/Heracles [U21] | 0:1 | ||||
| 9. Round | 05/11/2022 | Go Ahead Eagles [U21] | - | NAC Breda [U21] | 0:0 | ||||
| 10. Round | 12/11/2022 | NAC Breda [U21] | - | FC Den Bosch [U21] | 4:1 | ||||
| 12. Round | 26/11/2022 | NAC Breda [U21] | - | Vitesse [U21] | 1:1 |
Netherlands