| 1. Round | 08/07/2022 | CF América [Women] | - | Deportivo Toluca [Women] | 2:1 | ||||
| 10. Round | 29/08/2022 | Deportivo Toluca [Women] | - | Atlético San Luis [Women] | 2:0 | ||||
| 9. Round | 06/09/2022 | CF Monterrey [Women] | - | Deportivo Toluca [Women] | 5:2 | ||||
| 11. Round | 13/09/2022 | Mazatlán FC [Women] | - | Deportivo Toluca [Women] | 3:1 | ||||
| 12. Round | 19/09/2022 | Deportivo Toluca [Women] | - | Club Necaxa [Women] | 2:1 | ||||
| 13. Round | 22/09/2022 | Gallos Blancos [Women] | - | Deportivo Toluca [Women] | 2:3 | ||||
| 14. Round | 26/09/2022 | Deportivo Toluca [Women] | - | UANL Tigres [Women] | 1:4 |  |
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| 15. Round | 01/10/2022 | Club Tijuana [Women] | - | Deportivo Toluca [Women] | 1:0 | ||||
| 16. Round | 17/10/2022 | Deportivo Toluca [Women] | - | Puebla FC [Women] | 1:1 | ||||
| 17. Round | 24/10/2022 | Club León [Women] | - | Deportivo Toluca [Women] | 1:2 | |
Mexico