| 1. Round | 13/07/2018 | Cruz Azul [Women] | - | CF Pachuca [Women] | 1:2 | ||||
| 2. Round | 23/07/2018 | Lobos BUAP [Women] | - | Cruz Azul [Women] | 4:3 | ||||
| 3. Round | 27/07/2018 | Cruz Azul [Women] | - | CF América [Women] | 0:3 | ||||
| 4. Round | 07/08/2018 | Deportivo Toluca [Women] | - | Cruz Azul [Women] | 5:0 | ||||
| 6. Round | 17/08/2018 | Cruz Azul [Women] | - | Puebla FC [Women] | 0:0 | ||||
| 7. Round | 28/08/2018 | Club Tijuana [Women] | - | Cruz Azul [Women] | 1:1 |  |
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| 8. Round | 07/09/2018 | Cruz Azul [Women] | - | Pumas UNAM [Women] | 0:2 | ||||
| 9. Round | 14/09/2018 | CD Veracruz [Women] | - | Cruz Azul [Women] | 2:0 | ||||
| 10. Round | 18/09/2018 | CF Pachuca [Women] | - | Cruz Azul [Women] | 3:0 | ||||
| 11. Round | 21/09/2018 | Cruz Azul [Women] | - | Lobos BUAP [Women] | 2:3 | ||||
| 13. Round | 12/10/2018 | Cruz Azul [Women] | - | Deportivo Toluca [Women] | 0:3 | ||||
| 15. Round | 25/10/2018 | Puebla FC [Women] | - | Cruz Azul [Women] | 3:0 | ||||
| 16. Round | 28/10/2018 | Cruz Azul [Women] | - | Club Tijuana [Women] | 3:1 | ||||
| 17. Round | 03/11/2018 | Pumas UNAM [Women] | - | Cruz Azul [Women] | 0:1 | |
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| 18. Round | 16/11/2018 | Cruz Azul [Women] | - | CD Veracruz [Women] | 2:1 |
Mexico