| 7. Round | 25/09/2021 | FC Oberneuland | - | Hannover 96 II | 1:0 | ||||
| 5. Round | 29/09/2021 | Hannover 96 II | - | HSC Hannover | 2:1 | ||||
| 8. Round | 03/10/2021 | Lüneburger SK Hansa | - | Hannover 96 II | 0:1 |  |
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| 9. Round | 10/10/2021 | Hannover 96 II | - | VfV Hildesheim | 2:1 | |
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| 10. Round | 17/10/2021 | Hannover 96 II | - | SSV Jeddeloh II | 2:0 |  |
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| 11. Round | 23/10/2021 | Atlas Delmenhorst | - | Hannover 96 II | 1:0 | |
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| 13. Round | 06/11/2021 | Schwarz-Weiß Rehden | - | Hannover 96 II | 2:2 | ||||
| 14. Round | 14/11/2021 | HSC Hannover | - | Hannover 96 II | 1:5 | |
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| 6. Round | 20/11/2021 | Hannover 96 II | - | Werder Bremen II | 1:2 | ||||
| 16. Round | 28/11/2021 | Hannover 96 II | - | FC Oberneuland | 2:1 | |
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| 18. Round | 12/12/2021 | VfV Hildesheim | - | Hannover 96 II | 2:2 |
Germany