| Preliminary | 08/03/2022 | Sol de América | - | General Caballero DJLM | 0:3 |  |
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| Preliminary | 15/03/2022 | General Caballero DJLM | - | Sol de América | 2:1 | |
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| Group G | 06/04/2022 | General Caballero DJLM | - | Deportivo La Guaira | 1:1 |  |
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| Group G | 26/04/2022 | General Caballero DJLM | - | Ceará - CE | 0:2 | ||||
| Group G | 04/05/2022 | General Caballero DJLM | - | Independiente | 0:4 | |
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| Group G | 17/05/2022 | Ceará - CE | - | General Caballero DJLM | 6:0 | |
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| Group G | 26/05/2022 | Deportivo La Guaira | - | General Caballero DJLM | 0:1 |
Argentina