| 14. Round | 16/01/2021 | KF Skënderbeu | - | FK Partizani | 1:2 | ||||
| 15. Round | 20/01/2021 | KF Laçi | - | KF Skënderbeu | 1:1 | ||||
| 16. Round | 24/01/2021 | KF Skënderbeu | - | KF Apolonia Fier | 1:1 |  |
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| 17. Round | 30/01/2021 | KF Skënderbeu | - | FK Kukësi | 0:4 | ||||
| 18. Round | 06/02/2021 | KF Tiranë | - | KF Skënderbeu | 2:0 | ||||
| 22. Round | 03/03/2021 | KF Skënderbeu | - | KS Kastrioti | 0:1 | ||||
| 23. Round | 07/03/2021 | FK Partizani | - | KF Skënderbeu | 0:1 | |
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| 24. Round | 13/03/2021 | KF Skënderbeu | - | KF Laçi | 0:2 | ||||
| 25. Round | 21/03/2021 | KF Apolonia Fier | - | KF Skënderbeu | 1:2 |  |
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| 26. Round | 04/04/2021 | FK Kukësi | - | KF Skënderbeu | 0:1 | ||||
| 27. Round | 10/04/2021 | KF Skënderbeu | - | KF Tiranë | 0:0 | ||||
| 28. Round | 18/04/2021 | KF Skënderbeu | - | KF Teuta Durrës | 0:1 | |
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| 29. Round | 24/04/2021 | FK Vllaznia | - | KF Skënderbeu | 2:1 | ||||
| 30. Round | 28/04/2021 | KF Skënderbeu | - | KF Bylis Ballsh | 2:1 | ||||
| 31. Round | 02/05/2021 | KS Kastrioti | - | KF Skënderbeu | 0:2 | |
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| 33. Round | 13/05/2021 | KF Laçi | - | KF Skënderbeu | 0:0 | ||||
| 34. Round | 17/05/2021 | KF Skënderbeu | - | KF Apolonia Fier | 2:0 | ||||
| 35. Round | 21/05/2021 | KF Skënderbeu | - | FK Kukësi | 2:1 |
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