| 1. Round | 19/02/2020 | Real San Andrés | - | Cortuluá | 1:1 | ||||
| 2. Round | 24/09/2020 | Atlético Huila | - | Real San Andrés | 1:1 | ||||
| 2. Round | 01/10/2020 | Real San Andrés | - | Atlético Huila | 2:0 | ||||
| 3. Round | 22/10/2020 | Boyacá Chicó | - | Real San Andrés | 1:1 | ||||
| 3. Round | 29/10/2020 | Real San Andrés | - | Boyacá Chicó | 2:1 | ||||
| Round of 16 | 25/11/2020 | Real San Andrés | - | Deportivo Pasto | 2:4 pso |  |
Colombia