| 16. Round | 24/01/2021 | KVC Westerlo | - | RFC Seraing | 4:3 | ||||
| 17. Round | 31/01/2021 | KVC Westerlo | - | Lierse Kempenzonen | 2:0 | ||||
| 19. Round | 15/02/2021 | KVC Westerlo | - | Lommel SK | 1:1 |  |
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| 21. Round | 28/02/2021 | KVC Westerlo | - | KMSK Deinze | 4:0 | ||||
| 18. Round | 03/03/2021 | Club NXT | - | KVC Westerlo | 1:1 | ||||
| 22. Round | 07/03/2021 | RFC Seraing | - | KVC Westerlo | 1:1 | ||||
| 23. Round | 14/03/2021 | Lommel SK | - | KVC Westerlo | 1:0 | ||||
| 24. Round | 19/03/2021 | KVC Westerlo | - | Union Saint-Gilloise | 2:2 | ||||
| 25. Round | 04/04/2021 | Lierse Kempenzonen | - | KVC Westerlo | 0:0 | ||||
| 26. Round | 09/04/2021 | KVC Westerlo | - | RWD Molenbeek | 2:2 |  |
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| 27. Round | 19/04/2021 | KMSK Deinze | - | KVC Westerlo | 0:1 | ||||
| 28. Round | 24/04/2021 | KVC Westerlo | - | Club NXT | 1:1 |
Switzerland