| 1. Round | 11/07/2022 | Barcelona | - | Delfín SC | 0:1 | ||||
| 2. Round | 17/07/2022 | Técnico Universitario | - | Barcelona | 0:2 |  |
|||
| 3. Round | 25/07/2022 | Barcelona | - | 9 de Octubre | 2:2 | ||||
| 12. Round | 03/10/2022 | Barcelona | - | Guayaquil City | 1:1 | ||||
| 13. Round | 09/10/2022 | Deportivo Cuenca | - | Barcelona | 2:1 | ||||
| 14. Round | 17/10/2022 | Barcelona | - | Aucas | 0:2 | |
|||
| 15. Round | 23/10/2022 | Cumbayá | - | Barcelona | 1:1 |
Brazil