| 3. Round | 09/08/2020 | Atlético San Luis [U20] | - | Atlas Guadalajara [U20] | 1:0 |  |
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| 4. Round | 12/08/2020 | Club Tijuana [U20] | - | Atlético San Luis [U20] | 1:0 | ||||
| 8. Round | 03/09/2020 | CF Pachuca [U20] | - | Atlético San Luis [U20] | 0:2 | ||||
| 9. Round | 08/09/2020 | Atlético San Luis [U20] | - | Club Necaxa [U20] | 0:1 | ||||
| 10. Round | 13/09/2020 | Pumas UNAM [U20] | - | Atlético San Luis [U20] | 1:1 | ||||
| 11. Round | 20/09/2020 | Atlético San Luis [U20] | - | CF Monterrey [U20] | 0:5 | ||||
| 12. Round | 27/09/2020 | Atlético San Luis [U20] | - | Club León [U20] | 0:2 | ||||
| 13. Round | 03/10/2020 | UANL Tigres [U20] | - | Atlético San Luis [U20] | 1:0 | ||||
| 1. Round | 10/10/2020 | Atlético San Luis [U20] | - | FC Juárez [U20] | 4:0 | ||||
| 14. Round | 15/10/2020 | Atlético San Luis [U20] | - | Gallos Blancos [U20] | 0:1 | ||||
| 15. Round | 25/10/2020 | Santos Laguna [U20] | - | Atlético San Luis [U20] | 2:1 | ||||
| 16. Round | 29/10/2020 | Atlético San Luis [U20] | - | Mazatlán FC [U20] | 1:3 | ||||
| 17. Round | 06/11/2020 | Puebla FC [U20] | - | Atlético San Luis [U20] | 2:1 | ||||
| 2. Round | 14/11/2020 | Deportivo Toluca [U20] | - | Atlético San Luis [U20] | 3:0 |
Mexico