| 2. Round | 22/01/2022 | Deportivo Dongu | - | Leviatán FC | 2:1 | ||||
| 5. Round | 12/02/2022 | Leviatán FC | - | Escorpiones | 1:5 | ||||
| 6. Round | 19/02/2022 | Cafetaleros de Chiapas | - | Leviatán FC | 4:0 | ||||
| 3. Round | 23/02/2022 | Leviatán FC | - | Cañoneros FC | 0:3 | ||||
| 13. Round | 10/04/2022 | Lobos ULMX | - | Leviatán FC | 1:0 |
Mexico