| 1. Round | 13/03/2022 | Panathinaikos | - | AEK Athen | 1:1 | ||||
| 2. Round | 20/03/2022 | AEK Athen | - | PAOK Saloniki | 0:1 | ||||
| 3. Round | 03/04/2022 | Olympiakos Piraeus | - | AEK Athen | 1:1 | ||||
| 4. Round | 10/04/2022 | AEK Athen | - | Aris Saloniki | 1:2 | ||||
| 5. Round | 18/04/2022 | PAS Giannina | - | AEK Athen | 2:3 | ||||
| 6. Round | 01/05/2022 | PAOK Saloniki | - | AEK Athen | 1:1 | ||||
| 7. Round | 08/05/2022 | AEK Athen | - | Panathinaikos | 0:0 |  |
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| 8. Round | 11/05/2022 | AEK Athen | - | PAS Giannina | 3:0 | ||||
| 9. Round | 14/05/2022 | Aris Saloniki | - | AEK Athen | 3:2 |  |
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| 10. Round | 17/05/2022 | AEK Athen | - | Olympiakos Piraeus | 2:3 | |
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