6. Round | 02/05/2021 | Real Potosí | - | Nacional Potosí | 1:2 | ||||
8. Round | 10/07/2021 | Real Potosí | - | The Strongest | 1:3 | ||||
12. Round | 30/07/2021 | Real Potosí | - | Royal Pari | 1:3 | ||||
13. Round | 04/08/2021 | Independiente Petrolero | - | Real Potosí | 2:1 | ||||
14. Round | 09/08/2021 | CD Guabirá | - | Real Potosí | 3:0 | ||||
15. Round | 14/08/2021 | Real Potosí | - | Blooming | 3:1 | ||||
16. Round | 19/08/2021 | Real Potosí | - | Bolívar | 0:2 | ||||
18. Round | 12/09/2021 | Real Potosí | - | Real Tomayapo | 1:0 | ||||
19. Round | 17/09/2021 | San José | - | Real Potosí | 0:0 | ||||
20. Round | 22/09/2021 | Real Potosí | - | Real Santa Cruz | 3:0 | ||||
23. Round | 23/10/2021 | The Strongest | - | Real Potosí | 1:0 | ||||
24. Round | 26/10/2021 | Real Potosí | - | Jorge Wilstermann | 2:2 | ||||
26. Round | 21/11/2021 | Real Potosí | - | Always Ready | 3:2 | ||||
28. Round | 02/12/2021 | Real Potosí | - | Independiente Petrolero | 0:5 | ||||
29. Round | 05/12/2021 | Real Potosí | - | CD Guabirá | 1:3 |