| 1. Round | 14/07/2012 | Spartak Trnava | - | MFK Košice | 0:0 | ||||
| 3. Round | 29/07/2012 | Spartak Trnava | - | Spartak Myjava | 1:1 | ||||
| 4. Round | 05/08/2012 | Spartak Trnava | - | Slovan Bratislava | 0:1 | ||||
| 5. Round | 12/08/2012 | FK Senica | - | Spartak Trnava | 3:0 |  |
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| 6. Round | 18/08/2012 | Spartak Trnava | - | AS Trenčín | 0:3 | ||||
| 2. Round | 21/08/2012 | MŠK Žilina | - | Spartak Trnava | 1:1 | ||||
| 7. Round | 25/08/2012 | MFK Ružomberok | - | Spartak Trnava | 2:2 | ||||
| 8. Round | 02/09/2012 | Spartak Trnava | - | Zlaté Moravce | 0:5 | ||||
| 9. Round | 14/09/2012 | FC Nitra | - | Spartak Trnava | 1:3 | ||||
| 10. Round | 22/09/2012 | Spartak Trnava | - | FK Dukla Banská Bystrica | 1:0 | ||||
| 11. Round | 29/09/2012 | 1. FC Tatran Prešov | - | Spartak Trnava | 2:1 | ||||
| 12. Round | 05/10/2012 | MFK Košice | - | Spartak Trnava | 1:0 | ||||
| 13. Round | 20/10/2012 | Spartak Trnava | - | MŠK Žilina | 1:2 | ||||
| 14. Round | 27/10/2012 | Spartak Myjava | - | Spartak Trnava | 2:2 | ||||
| 15. Round | 02/11/2012 | Slovan Bratislava | - | Spartak Trnava | 0:1 | |
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| 16. Round | 10/11/2012 | Spartak Trnava | - | FK Senica | 1:1 | |
Slovakia