| 5. Round | 12/03/2021 | Boca Juniors II | - | River Plate II | 0:1 | ||||
| 6. Round | 19/03/2021 | Boca Juniors II | - | Talleres de Córdoba II | 2:2 | ||||
| 7. Round | 29/03/2021 | Independiente II | - | Boca Juniors II | 1:1 | ||||
| 8. Round | 02/04/2021 | Boca Juniors II | - | Defensa y Justicia II | 1:0 | ||||
| 9. Round | 09/04/2021 | Unión de Santa Fe II | - | Boca Juniors II | 2:3 | ||||
| 10. Round | 16/04/2021 | Boca Juniors II | - | Atlético Tucumán II | 3:1 | ||||
| 12. Round | 30/04/2021 | Boca Juniors II | - | Lanús II | 3:2 | ||||
| 13. Round | 07/05/2021 | Patronato de Paraná II | - | Boca Juniors II | 0:2 |  |
Argentina