| 4. Round | 27/02/2022 | Palestino | - | Universidad Católica | 3:2 | ||||
| 6. Round | 12/03/2022 | Universidad Católica | - | Everton | 0:1 | ||||
| 8. Round | 02/04/2022 | Universidad Católica | - | Universidad de Chile | 2:1 | ||||
| 12. Round | 08/05/2022 | Ñublense | - | Universidad Católica | 4:0 |  |
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| 14. Round | 21/05/2022 | Audax Italiano | - | Universidad Católica | 3:2 |  |
| Lucas Santiago Melano | |
| Born: | 01.03.1993 |
| Place of birth: |
Hernando, 
Argentina |
| Nationality: |
Argentina
Italy |
| Height: | 187 cm |
| Weight: | 72 kg |
| Position(s): | Centre Forward Right Midfielder |
| Foot: | right |
