| 3. Round | 30/08/1980 | TJ Bohemians ČKD Praha | - | TJ Spartak TAZ Trnava | 3:0 | ||||
| 7. Round | 04/10/1980 | TJ Plastika Nitra | - | TJ Spartak TAZ Trnava | 1:0 | ||||
| 8. Round | 12/10/1980 | TJ Spartak TAZ Trnava | - | TJ Lokomotíva Košice | 1:3 |  |
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| 9. Round | 19/10/1980 | TJ Zbrojovka Brno | - | TJ Spartak TAZ Trnava | 0:0 | ||||
| 10. Round | 24/10/1980 | SK Slavia Praha IPS | - | TJ Spartak TAZ Trnava | 4:1 | ||||
| 11. Round | 31/10/1980 | TJ Spartak TAZ Trnava | - | TJ Sparta ČKD Praha | 1:0 | ||||
| 12. Round | 09/11/1980 | TJ Slovan ChZJD Bratislava | - | TJ Spartak TAZ Trnava | 1:2 | ||||
| 13. Round | 23/11/1980 | TJ Spartak TAZ Trnava | - | ASVŠ Dukla Banská Bystrica | 2:0 | |
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| 14. Round | 07/12/1980 | TJ Tatran Prešov | - | TJ Spartak TAZ Trnava | 4:1 | ||||
| 15. Round | 14/12/1980 | TJ Spartak TAZ Trnava | - | TJ ZŤS Košice | 1:0 | ||||
| 16. Round | 22/02/1981 | TJ Spartak TAZ Trnava | - | TJ Spartak ZVÚ Hradec Králové | 1:0 | ||||
| 18. Round | 08/03/1981 | TJ Spartak TAZ Trnava | - | TJ Bohemians ČKD Praha | 1:0 | ||||
| 19. Round | 15/03/1981 | TJ Internacionál Slovnaft Bratislava | - | TJ Spartak TAZ Trnava | 2:1 |
Slovakia