| 2. Round | 23/04/2022 | Chacaritas FC [U19] | - | América de Quito [U19] | 2:1 | ||||
| 5. Round | 13/05/2022 | América de Quito [U19] | - | El Nacional [U19] | 1:4 | ||||
| 6. Round | 21/05/2022 | Mushuc Runa [U19] | - | América de Quito [U19] | 1:1 | ||||
| 9. Round | 11/06/2022 | América de Quito [U19] | - | Chacaritas FC [U19] | 0:2 | ||||
| 10. Round | 09/07/2022 | Cumbayá [U19] | - | América de Quito [U19] | 1:1 | ||||
| 11. Round | 15/07/2022 | América de Quito [U19] | - | Macará [U19] | 1:5 |
Ecuador