| 2. Round | 29/01/2019 | Atlético Huila | - | Unión Magdalena | 1:1 | ||||
| 3. Round | 02/02/2019 | Unión Magdalena | - | La Equidad | 1:0 |  |
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| 4. Round | 10/02/2019 | Independiente Medellín | - | Unión Magdalena | 1:1 | ||||
| 5. Round | 20/02/2019 | Deportivo Cali | - | Unión Magdalena | 2:1 |  |
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| 6. Round | 24/02/2019 | Unión Magdalena | - | Atlético Nacional | 1:0 | ||||
| 8. Round | 03/03/2019 | Unión Magdalena | - | Deportivo Pasto | 1:0 | ||||
| 9. Round | 10/03/2019 | Cúcuta Deportivo | - | Unión Magdalena | 3:1 | |
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| 10. Round | 17/03/2019 | Unión Magdalena | - | Atlético Junior | 1:1 | |
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| 11. Round | 24/03/2019 | Deportes Tolima | - | Unión Magdalena | 1:0 | ||||
| 13. Round | 27/03/2019 | Atlético Junior | - | Unión Magdalena | 1:1 | |
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| 12. Round | 31/03/2019 | Unión Magdalena | - | Alianza Petrolera | 1:1 | |
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| 14. Round | 06/04/2019 | Unión Magdalena | - | Patriotas FC | 4:0 | |
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| 15. Round | 13/04/2019 | Águilas Doradas | - | Unión Magdalena | 0:1 | ||||
| 16. Round | 18/04/2019 | Unión Magdalena | - | América de Cali | 0:3 | ||||
| 18. Round | 27/04/2019 | Unión Magdalena | - | Santa Fe | 3:1 | |
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| 20. Round | 05/05/2019 | Unión Magdalena | - | Once Caldas | 1:0 | |
Colombia