| 1. Round | 28/07/2012 | Libertad | - | Club Nacional | 1:0 | ||||
| 2. Round | 03/08/2012 | Tacuary | - | Libertad | 1:1 | ||||
| 3. Round | 12/08/2012 | Libertad | - | Guaraní | 0:0 | ||||
| 4. Round | 19/08/2012 | Club Olimpia | - | Libertad | 2:2 | ||||
| 5. Round | 25/08/2012 | Libertad | - | Sol de América | 1:1 | ||||
| 6. Round | 29/08/2012 | Sportivo Carapeguá | - | Libertad | 2:0 | ||||
| 7. Round | 02/09/2012 | Libertad | - | Club Rubio Ñu | 3:0 | ||||
| 8. Round | 16/09/2012 | Cerro Porteño | - | Libertad | 3:3 | ||||
| 9. Round | 23/09/2012 | Libertad | - | Independiente CG | 3:0 | ||||
| 10. Round | 30/09/2012 | Libertad | - | Cerro de Franco | 3:0 | ||||
| 11. Round | 07/10/2012 | Sportivo Luqueño | - | Libertad | 0:2 | ||||
| 12. Round | 20/10/2012 | Club Nacional | - | Libertad | 1:2 | ||||
| 14. Round | 30/10/2012 | Guaraní | - | Libertad | 0:2 | ||||
| 15. Round | 03/11/2012 | Libertad | - | Club Olimpia | 1:1 | ||||
| 17. Round | 17/11/2012 | Libertad | - | Sportivo Carapeguá | 2:1 |
Paraguay