| 17. Round | 19/01/2019 | Tuxtla FC | - | Albinegros Orizaba | 3:0 | ||||
| 18. Round | 26/01/2019 | Real Zamora | - | Tuxtla FC | 2:0 | ||||
| 22. Round | 23/02/2019 | Tuzos de la UAZ | - | Tuxtla FC | 1:0 | ||||
| 24. Round | 10/03/2019 | Club Irapuato | - | Tuxtla FC | 2:0 | ||||
| 25. Round | 16/03/2019 | Tuxtla FC | - | Reboceros de La Piedad | 0:0 | ||||
| 26. Round | 23/03/2019 | Inter Playa | - | Tuxtla FC | 1:2 |  |
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| 27. Round | 30/03/2019 | Tuxtla FC | - | Yalmakan FC | 4:1 | ||||
| 28. Round | 05/04/2019 | CF América II | - | Tuxtla FC | 1:1 | ||||
| 29. Round | 12/04/2019 | Cruz Azul Hidalgo | - | Tuxtla FC | 0:0 | ||||
| 30. Round | 20/04/2019 | Tuxtla FC | - | Pumas UNAM II | 1:1 | |
Mexico