| Group 8 | 07/03/2017 | Deportes Iquique | - | Guaraní | 0:1 | ||||
| Group 8 | 12/04/2017 | Guaraní | - | Zamora FC | 3:1 | ||||
| Group 8 | 20/04/2017 | Guaraní | - | Grêmio Porto Alegre | 1:1 | ||||
| Group 8 | 05/05/2017 | Zamora FC | - | Guaraní | 1:3 | ||||
| Round of 16 | 05/07/2017 | Guaraní | - | River Plate | 0:2 |  |
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| Round of 16 | 09/08/2017 | River Plate | - | Guaraní | 1:1 |
Paraguay