| 5. Round | 27/07/2022 | Coyotes de Tlaxcala | - | CF Monterrey II | 1:1 | ||||
| 6. Round | 02/08/2022 | Alacranes de Durango | - | Coyotes de Tlaxcala | 3:0 | ||||
| 7. Round | 10/08/2022 | Atlético La Paz | - | Coyotes de Tlaxcala | 2:2 | ||||
| 13. Round | 21/09/2022 | Coyotes de Tlaxcala | - | Tepatitlán | 2:1 | ||||
| 14. Round | 24/09/2022 | Alebrijes de Oaxaca | - | Coyotes de Tlaxcala | 3:0 |
Mexico