| 2. Round | 16/01/2021 | Cruz Azul [U20] | - | Puebla FC [U20] | 1:0 | ||||
| 4. Round | 30/01/2021 | Cruz Azul [U20] | - | Gallos Blancos [U20] | 0:0 | ||||
| 5. Round | 05/02/2021 | Club Necaxa [U20] | - | Cruz Azul [U20] | 0:1 | ||||
| 6. Round | 13/02/2021 | UANL Tigres [U20] | - | Cruz Azul [U20] | 2:0 | ||||
| 13. Round | 02/04/2021 | FC Juárez [U20] | - | Cruz Azul [U20] | 0:1 | ||||
| 3. Round | 07/04/2021 | CF Pachuca [U20] | - | Cruz Azul [U20] | 0:0 | ||||
| 14. Round | 10/04/2021 | Cruz Azul [U20] | - | Deportivo Guadalajara [U20] | 0:1 | ||||
| 16. Round | 24/04/2021 | Cruz Azul [U20] | - | Atlético San Luis [U20] | 0:1 | ||||
| 17. Round | 01/05/2021 | Cruz Azul [U20] | - | Club Tijuana [U20] | 0:1 |
Mexico